The aim of this study was to examine the actual effects of lifetime physical activity on the incidence and severity of acute coronary syndromes (ACS), using biochemical markers (cardiac troponin I released and MB fraction of total creatine phosphokinase) as indices of myocardial necrosis. Among 2,172 patients with ACS, the authors found that physical activity was negatively associated with ACS severity. Furthermore, they showed that physical activity was also associated with a reduction of in-hospital mortality rates and better short-term prognosis. In conclusion, the authors noted that in combination with other cardioprotective methods, incorporating exercise into one’s lifestyle may be an effective way to gain additional cardioprotection and reduce both morbidity and mortality with respect to naturally occurring ACS.
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