The aim of this study by Chatzinikolaou et al. was to monitor, in lean and obese men, adipose tissue triacylglycerol lipase activity (TGLA) along with metabolic and hormonal responses to resistance exercise. For that purpose, nine lean and eight obese healthy untrained men performed 30 minutes of circuit resistance exercise in the fasting state. The authors documented that adipose tissue TGLA peaked at 5 minutes in lean men (rising from 0.32 ± 0.27 to 5.82 ± 1.32 mmol*kg-1*min-1) and at 10 minutes in obese men (from 0.36 ± 0.23 to 5.88 ± 2.32 mmol*kg-1*min-1). Moreover, obese men had lower energy expenditure during exercise relative to body mass and higher respiratory exchange ratio in comparison with lean men. Plasma insulin did not change in the lean but increased in the obese men following the first exercise cycle and remained elevated thereafter. The authors also observed a delay in resistance exercise-induced lipolytic activation in the obese men. In conclusion, resistance exercise upregulated adipose tissue lipolysis and enhanced energy expenditure in lean and obese men, with a delayed lipolytic activation in the obese men.
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