Relationship between total and high molecular weight adiponectin levels and plasma nonesterified fatty acid tolerance during enhanced intravascular triacylglycerol lipolysis in men.

Description

The objective of this paper was to determine whether total and high molecular weight (HMW) plasma adiponectin levels were associated with plasma nonesterified fatty acid (NEFA) levels and appearance as well as with total triglyceride lipolytic rate during enhanced intravascular triglyceride lipolysis in 15 healthy men. Results of this study revealed that there was a significant inverse relationship between adiponectin levels and NEFA concentrations or appearance rate during intralipid infusion. However, this relationship appeared to be dependent on the effect of increased fat mass on both adiponectin and NEFA appearance rate. Moreover, adiponectin concentrations were positively associated with total triglyceride lipolytic capacity, expressed as a function of nonlean mass. Finally, HMW adiponectin was not a better marker of adipose tissue metabolic function than total adiponectin concentrations.