Usefulness of serum high-density lipoprotein cholesterol level as an independent predictor of one-year mortality after percutaneous coronary interventions.

Description

Although there is evidence that a low HDL cholesterol concentration is predictive of coronary artery disease progression and is associated with cardiovascular events, whether a low HDL cholesterol concentration is a useful prognostic indicator after percutaneous coronary intervention is uncertain. In this sample of 4,088 patients who underwent percutaneous coronary intervention, one-year mortality and coronary revascularization were significantly higher in patients with very low HDL cholesterol concentrations (<0.90 mmol/l) compared with the other groups. The one-year mortality rate was significantly greater (almost doubled) in patients with very low HDL cholesterol levels in a multivariable analysis taking into account independent predictors of outcome. Thus, this study confirmed that there is an association between HDL cholesterol and one-year mortality after percutaneous coronary intervention.