The effect of 2 lifestyle interventions (nutritional recommendations, weight loss and increased physical activity vs. similar recommendations plus advice on the DASH diet) on blood pressure and 10-year estimated coronary heart disease (CHD) risk (Framingham risk score) was examined in a sample of 810 individuals with untreated prehypertension or stage I hypertension compared to a control group (advice only). Compared to the control group, the relative risk ratio of 6 months vs. baseline 10-year CHD risk was 0.86 (95% CI: 0.81-0.91, p<0.001) for individuals who received the nutritional, weight loss and physical activity recommendations and 0.88 (95% CI: 0.83-0.94, p<0.001) for individuals who also received the DASH diet recommendations. Results were consistent across several subgroups of subjects classified on the basis of age, sex and baseline CHD risk factors and persisted at 18 months.
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