Dietary intake of saturated fatty acids and mortality from cardiovascular disease in Japanese: the Japan Collaborative Cohort Study for Evaluation of Cancer Risk (JACC) Study.
Am J Clin Nutr 2010;92:759-65
Yamagishi K, Iso H, Yatsuya H, Tanabe N, Date C, Kikuchi S, Yamamoto A, Inaba Y, Tamakoshi A, JACC Study Group
The aim of this study was to examine the association between saturated fatty acid (SFA) intake and mortality from stroke in a Japanese cohort. A total of 58,453 Japenese men and women from the Japan Collaborative Cohort Study for Evaluation of Cancer Risk (JACC Study) were analyzed. Participants were aged 40-79 years at baseline and were followed up for 14.1 years during which 976 deaths due to stroke were reported. Results revealed an inverse association between dietary SFA intake and stroke mortality, for both ischemic stroke and intraparenchymal hemorrhage. These results are not concordant with what was observed in the more general population. The authors suggest that the discrepancy of the results between Japanese individuals and Western countries might be explained in part by a lower distribution of SFA intake in the Japanese population.