The objective of this study was to investigate the effect of postprandial time on the associations and predictive value of nonfasting lipid levels and cardiovascular disease (CVD) risk in patients with diabetes. The cohort included 1,337 participants with diabetes from the Dutch and German (Potsdam) contributions to the European Prospective Investigation into Cancer and Nutrition. The UKPDS risk engine was used to calculate a 5-year CVD risk. Results revealed that nonfasting lipid concentrations were associated with CVD risk independent of postprandial time. Only triglyceride concentrations were found to increase following a meal. CVD risk prediction was not affected by postprandial time. These data indicate that a fasting state is not necessary when examining the relationship of lipids to CVD risk in patients with diabetes.
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