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Key Publications January 16, 2009

Clinical risk factors, DNA variants, and the development of type 2 diabetes.

N Engl J Med 2008;359:2220-32

Lyssenko V, Jonsson A, Almgren P et al.
Diabetes Genetics Insulin Resistance
Key Publications January 15, 2009

Genotype score in addition to common risk factors for prediction of type 2 diabetes.

N Engl J Med 2008;359:2208-19

Meigs JB, Shrader P, Sullivan LM et al.
Diabetes Genetics Prevention
Key Publications October 30, 2008

Physical activity and the association of common FTO gene variants with body mass index and obesity.

Arch Intern Med 2008;168:1791-7

Rampersaud E, Mitchell BD, Pollin TI et al.
Genetics Obesity Physical Activity/Exercise
Key Publications October 29, 2008

Obesity associated genetic variation in FTO is associated with diminished satiety.

J Clin Endocrinol Metab 2008;93:3640-3

Wardle J, Carnell S, Haworth CM, Farooqi IS, O'Rahilly S, Plomin R.
Genetics Nutrition Obesity
Key Publications October 26, 2008

Replication study of 10 genetic polymorphisms associated with coronary heart disease in a specific high-risk population with familial hypercholesterolemia.

Eur Heart J 2008;29:2195-201

Van der Net JB, Oosterveer DM, Versmissen J et al.
Cardiovascular Disease Genetics Lipids/Lipoproteins
Key Publications August 22, 2008

Genetic screening of the LPL gene in hypertriglyceridaemic patients.

Atherosclerosis 2008;199:187-92

Wright WT, Young IS, Nicholls DP, Graham CA
Cardiovascular Disease Genetics Lipids/Lipoproteins
Key Publications July 10, 2008

Relationship of paraoxonase 1 (PON1) gene polymorphisms and functional activity with systemic oxidative stress and cardiovascular risk.

JAMA 2008;299:1265-76

Bhattacharyya T, Nicholls SJ, Topol EJ et al.
Cardiovascular Disease Genetics
Key Publications June 3, 2008

PPARgamma mRNA expression is reduced in peripheral blood mononuclear cells after fat overload in patients with metabolic syndrome.

J Nutr 2008;138:903-7

Macias-Gonzalez M, Cardona F, Queipo-Ortuño M, Bernal R, Martin M, Tinahones FJ
Genetics Lipids/Lipoproteins Metabolic Syndrome
Key Publications May 24, 2008

Promoter adiponectin polymorphisms and waist/hip ratio variation in a prospective French adults study.

Int J Obes (Lond) 2008;32:669-75

Dolley G, Bertrais S, Frochot V et al.
Abdominal Obesity/Body Fat Distribution Adipokines Genetics
Key Publications May 5, 2008

LDL-cholesterol concentrations: a genome-wide association study.

Lancet 2008;371:483-91

Sandhu MS, Waterworth DM, Debenham SL et al.
Epidemiology Genetics Lipids/Lipoproteins
Key Publications May 5, 2008

Genomics: the next step to elucidate the etiology of calcific aortic valve stenosis.

J Am Coll Cardiol 2008;51:1327-36

Bossé Y, Mathieu P, Pibarot P
Cardiovascular Disease Clinical Cardiology Genetics
Key Publications May 2, 2008

Simvastatin with or without ezetimibe in familial hypercholesterolemia.

N Engl J Med 2008;358:1431-43

Kastelein JJ, Akdim F, Stroes ES et al.
Cardiovascular Disease Genetics Lipids/Lipoproteins
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