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Key Publications August 8, 2009

Abdominal obesity and all-cause and cardiovascular mortality in end-stage renal disease.

J Am Coll Cardiol 2009;53:1265-72

Postorino M, Marino C, Tripepi G, Zoccali C, CREDIT (Calabria Registry of Dialysis and Transplantation) Working Group

Description

This study tested the predictive power for all-cause and cardiovascular disease death of waist circumference as a surrogate marker of abdominal obesity in patients with end-stage renal disease. The incidence rate of overall and cardiovascular disease death was highest in patients with lower body mass index (BMI) values (below the median) but higher waist circumference values (greater than the median). The incidence rate was lowest in patients with higher BMI but lower waist circumference values. Adjusting for traditional and emerging risk factors modestly influenced the relationship between waist circumference and all-cause and cardiovascular disease mortality. Thus, abdominal obesity is associated with an increased risk of all-cause and cardiovascular disease mortality in patients with end-stage renal disease.
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