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Key Publications October 12, 2007

Long-term impact of diabetes and its comorbidities in patients undergoing isolated primary coronary artery bypass graft surgery.

Circulation 2007;116:I220-5

Mohammadi S, Dagenais F, Mathieu P et al.

Description

This study examined the impact of diabetes and related complications (chronic renal failure, peripheral vascular disease, low ejection fraction (<35%)) on the long-term survival of patients who underwent primary isolated coronary artery bypass graft surgery. This retrospective study was conducted in 9,125 survivors (6,581 nondiabetics and 2,544 diabetics (71% had type 2 diabetes)) of isolated coronary artery bypass graft surgery. Type 2 diabetes was not an independent risk factor for long-term cardiac-related death after coronary artery bypass graft surgery. Long-term survival of type 2 diabetic patients in the absence of comorbidities was excellent. Patients with type 1 diabetes had a worse cardiac-specific survival rate compared to patients with type 2 diabetes. Furthermore, in diabetic and nondiabetic patients, the 10 year survival rate was adversely affected by the need for insulin therapy and/or the number of metabolic complications (chronic renal failure, peripheral vascular disease, low ejection fraction).

Categories

Diabetes
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