Low-fat versus low-carbohydrate weight reduction diets: effects on weight loss, insulin resistance, and cardiovascular risk: a randomized control trial.

Description

This study compared two types of diet (low-carbohydrate vs. low-fat) on weight loss, insulin resistance and cardiovascular risk in 24 overweight/obese subjects in an 8-week randomized controlled trial. The two groups showed significant weight loss (>7%; p<0.01), with no difference between groups. The two diets had comparable effects on insulin sensitivity. However, there was a significant difference in systemic arterial stiffness between the diets suggesting a potentially negative effect of a low-carbohydrate diet on long-term vascular health.