In this video, Dr. Arya Sharma notes that people do not necessarily have to lose a large percentage of their body weight in order to get clinical benefits. Patients can get significant beneficial effects by losing only 5% of their body weight, which could be associated with a 20% to 30% loss of intra-abdominal (visceral) fat. Regarding longevity, Dr. Sharma acknowledges that obesity surgery is one of the most powerful treatments available for very obese patients. Dr. Barbara Howard discusses the importance of a healthy diet and how this has a direct effect on cardiovascular risk. Dr. Edward Horton and Dr. Jean-Pierre Després sum up by stating that reshaping nutritional habits and physical activity are key to achieving and maintaining body weight loss and to reducing cardiometabolic risk because of how this approach spurs a selective loss of “bad” abdominal fat.