Assessing Cardiometabolic Risk

Evaluating CMR

Assessing Cardiometabolic Risk

A number of groups and organizations have emphasized the importance of considering all known risk factors when assessing global cardiovascular disease (CVD) risk. However, the risk assessment algorithms used mainly take into account traditional risk factors such as age, sex, family history, blood pressure, smoking, cholesterol (both LDL and HDL), and diabetes. With abdominal obesity now at epidemic proportions, many individuals are at increased relative risk of CVD because of the presence of a constellation of metabolic abnormalities often referred to as the metabolic syndrome. It has been suggested that the CVD risk of abdominal obesity/metabolic syndrome may be independent from or go beyond the risk predicted by traditional risk factors. A model has therefore been developed to incorporate abdominal obesity/metabolic syndrome risk into the risk conferred by traditional risk factors. This global CVD risk is defined as global cardiometabolic risk, and new algorithms will be necessary to capture the additional risk of abdominal obesity/metabolic syndrome.

For more detailed information on the metabolic syndrome and on global cardiometabolic risk, the reader is invited to consult several review papers [1-3].

References

  1. Després JP and Lemieux I. Abdominal obesity and metabolic syndrome. Nature 2006; 444: 881-7.

    PubMed ID: 17167477
  2. Després JP, Lemieux I, Bergeron J, et al. Abdominal obesity and the metabolic syndrome: contribution to global cardiometabolic risk. Arterioscler Thromb Vasc Biol 2008; 28: 1039-49.

    PubMed ID: 18356555
  3. Després JP. From syndrome X to cardiometabolic risk: clinical and public health implications. Proc Nutr Soc 2020; 79: 4-10.

    PubMed ID: 31317841
Reference 1 CLOSECLOSE

Després JP and Lemieux I. Abdominal obesity and metabolic syndrome. Nature 2006; 444: 881-7.

PubMed ID: 17167477
Reference 2 CLOSECLOSE

Després JP, Lemieux I, Bergeron J, et al. Abdominal obesity and the metabolic syndrome: contribution to global cardiometabolic risk. Arterioscler Thromb Vasc Biol 2008; 28: 1039-49.

PubMed ID: 18356555
Reference 3 CLOSECLOSE

Després JP. From syndrome X to cardiometabolic risk: clinical and public health implications. Proc Nutr Soc 2020; 79: 4-10.

PubMed ID: 31317841