This study investigated the effects of drinking skin milk in comparison with a fruit drink at breakfast on self-reported postmeal satiety and energy intake measured at the following lunch. In this randomized cross-over study, overweight men (n=13) and women (n=21) attended two sessions separated by one week. A fixed-energy breakfast together with a 600 ml skim milk or fruit drink had to be consumed. After the consumption of skim milk, participants consumed less energy at lunch than after drinking fruit juice. Moreover, self-reports of satiety were higher throughout the morning after the consumption of skim milk as compared to fruit drink. Therefore, the consumption of skim milk in comparison to fruit drink leaded to a reduction in energy intake at the subsequent meal together with a higher perception of satiety.