Long-term cardiovascular risk in type 2 diabetic compared with nondiabetic first acute myocardial infarction patients: a population-based cohort study in southern Europe.
Diabetes Care 2010;33:2004-9
Cano JF, Baena-Diez JM, Franch J, Vila J, Tello S, Sala J, Elosua R, Marrugat J, REGICOR and GEDAPS Investigators
This prospective study was conducted to compare the long-term cardiovascular risk between patients with type 2 diabetes and patients with first acute myocardial infarction as well as to assess the impact of diabetes duration, type of treatment and glycemic control at baseline. The population-based cohort consisted of 4,410 patients aged 30-74 years and included 2,260 patients with type 2 diabetes without coronary heart disease and 2,150 with first acute myocardial infarction without diabetes. Results indicated that patients with type 2 diabetes had lower adjusted 10-year cardiovascular mortality and coronary heart disease incidence risk than myocardial infarction patients. Several factors such as the type of treatment, the duration of diabetes and the glycemic control had an impact on the 10-year prognosis for cardiovascular risk in patients with type 2 diabetes. These results suggest that type 2 diabetes is not a coronary heart disease equivalent for cardiovascular risk in Southern Europe.