The aim of this study was to determine the respective contributions of cardiorespiratory fitness (CRF) and different measures of adiposity to all-cause mortality in women. Participants in the present study included 11,335 women who were followed for a mean time of 12.3±8.2 years and during which 292 deaths were recorded. Analyses revealed that CRF was strongly and inversely associated with all-cause mortality independently of several confounding factors, including the adiposity measures. Moreover, fit women were characterized with lower risk of death irrespective of their level of body mass index, adiposity or waist circumference. Thus, these results suggest a protective role of CRF on risk of all-cause mortality in women.
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