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Key Publications November 10, 2020

Low-density lipoproteins cause atherosclerotic cardiovascular disease: pathophysiological, genetic, and therapeutic insights: a consensus statement from the European Atherosclerosis Society Consensus Panel.

Eur Heart J. 2020;41:2313-2330

Borén J, Chapman MJ, Krauss RM, Packard CJ, Bentzon JF, Binder CJ, Daemen MJ, Demer LL, Hegele RA, Nicholls SJ, Nordestgaard BG, Watts GF, Bruckert E et al.
Cardiovascular Disease Genetics Lipids/Lipoproteins
Key Publications November 9, 2020

Triglycerides and remnant cholesterol associated with risk of aortic valve stenosis: Mendelian randomization in the Copenhagen General Population Study.

Eur Heart J. 2020;41:2288-2299.

Kaltoft M, Langsted A, Nordestgaard BG
Cardiovascular Disease Genetics Lipids/Lipoproteins
Key Publications November 6, 2020

Polygenic risk scores and physical activity.

Med Sci Sports Exerc. 2020;52:1518-1524

Kujala UM, Palviainen T, Pesonen P, Waller K, SillanpÄÄ E, NiemelÄ M, Kangas M, VÄhÄ-YpyÄ H, SievÄnen H, Korpelainen R, JÄmsÄ T, MÄnnikkÖ M, Kaprio J
Genetics Physical Activity/Exercise Prevention
Key Publications November 3, 2020

Alcohol consumption and cardiovascular disease: A Mendelian randomization study.

Circ Genom Precis Med. 2020;13:e002814

Larsson SC, Burgess S, Mason AM, Michaëlsson K
Cardiovascular Disease Genetics Nutrition
Key Publications October 29, 2020

Is type 2 diabetes causally associated with cancer risk? Evidence from a two-sample Mendelian randomization study.

Diabetes. 2020;69:1588-1596

Yuan S, Kar S, Carter P, Vithayathil M, Mason AM, Burgess S, Larsson SC
Cancer Diabetes Genetics
Key Publications October 26, 2020

Identification of type 2 diabetes loci in 433,540 East Asian individuals.

Nature. 2020;582:240-245

Spracklen CN, Horikoshi M, Kim YJ, Lin K, Bragg F, Moon S, Suzuki K, Tam CHT, Tabara Y, Kwak SH, Takeuchi F et al.
Diabetes Epidemiology Genetics
Key Publications October 23, 2020

Polygenic risk, fitness, and obesity in the Coronary Artery Risk Development In young Adults (CARDIA) Study.

JAMA Cardiol. 2020;5:40-8

Murthy VL, Xia R, Baldridge AS, Carnethon MR, Sidney S, Bouchard C, Sarzynski MA, Lima JAC, Lewis GD, Shah SJ, Fornage M, Shah RV
Age Genetics Obesity
Key Publications October 22, 2020

Opportunities and challenges for polygenic risk scores in prognostication and prevention of cardiovascular disease.

JAMA Cardiol. 2020;5:399-400

O'Donnell CJ
Cardiovascular Disease Genetics Prevention
Key Publications September 23, 2020

Gene polymorphisms of Patatin-like phospholipase domain containing 3 (PNPLA3), adiponectin, leptin in diabetic obese patients.

PLoS One. 2020;15:e0234465

Aly O, Zaki HH, Herzalla MR, Fathy A, Raafat N, Hafez MM
Diabetes Genetics Obesity
Key Publications September 21, 2020

Evaluating the relationship between circulating lipoprotein lipids and apolipoproteins with risk of coronary heart disease: A multivariable Mendelian randomisation analysis.

PLoS Med. 2020;17:e1003062

Richardson TG, Sanderson E, Palmer TM, Ala-Korpela M, Ference BA, Davey Smith G, Holmes MV
Cardiovascular Disease Genetics Lipids/Lipoproteins
Key Publications September 18, 2020

Phenotypic and lifestyle determinants of HbA1c in the general population-The Hoorn Study.

PLoS One. 2020;15:e0233769

Wisgerhof W, Ruijgrok C, den Braver NR, Borgonjen-van den Berg KJ, van der Heijden AAWA, Elders PJM, Beulens JWJ, Alssema M
Clinical Trials Genetics Metabolism: Human Studies
Key Publications September 17, 2020

Smoking-by-genotype interaction in type 2 diabetes risk and fasting glucose.

PLoS One. 2020;15:e0230815

Wu P, Rybin D, Bielak LF, Feitosa MF, Franceschini N, Li Y, Lu Y, Marten J, Musani SK, Noordam R, Raghavan S et al.
Diabetes Genetics Smoking
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