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International Chair on Cardiometabolic Risk
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Key Publications July 26, 2012

Vitamin D dependent effects of APOA5 polymorphisms on HDL cholesterol.

Atherosclerosis 2012;222:167-74

Shirts BH, Howard MT, Hasstedt SJ, Nanjee MN, Knight S, Carlquist JF, Anderson JL, Hopkins PN, Hunt SC
Genetics Lipids/Lipoproteins Metabolism: Human Studies
Key Publications July 25, 2012

Global variation in the prevalence of elevated cholesterol in outpatients with established vascular disease or 3 cardiovascular risk factors according to national indices of economic development and health system performance.

Circulation 2012;125:1858-69

Venkitachalam L, Wang K, Porath A, Corbalan R, Hirsch AT, Cohen DJ, Smith SC Jr, Ohman EM, Steg PG, Bhatt DL, Magnuson EA; REACH Registry Investigators
Epidemiology Lipids/Lipoproteins
Key Publications July 25, 2012

Genetic determinants of statin-induced low-density lipoprotein cholesterol reduction: the Justification for the Use of Statins in Prevention: an Intervention Trial Evaluating Rosuvastatin (JUPITER) trial.

Circ Cardiovasc Genet 2012;5:257-64

Chasman DI, Giulianini F, MacFadyen J, Barratt BJ, Nyberg F, Ridker PM
Genetics Lipids/Lipoproteins
Key Publications July 25, 2012

Genome-wide screen for metabolic syndrome susceptibility Loci reveals strong lipid gene contribution but no evidence for common genetic basis for clustering of metabolic syndrome traits.

Circ Cardiovasc Genet 2012;5:242-9

Kristiansson K, Perola M, Tikkanen E, Kettunen J, Surakka I, Havulinna AS, Stancáková A, Barnes C, Widen E, Kajantie E, Eriksson JG, Viikari J, Kähönen M, Lehtimäki T, Raitakari OT, Hartikainen AL, Ruokonen A, Pouta A, Jula A, Kangas AJ, Soininen P, Ala-Korpela M, Männistö S, Jousilahti P, Bonnycastle LL, Järvelin MR, Kuusisto J, Collins FS, Laakso M, Hurles ME, Palotie A, Peltonen L, Ripatti S, Salomaa V
Genetics Lipids/Lipoproteins Metabolic Syndrome
Key Publications July 24, 2012

On-treatment non-high-density lipoprotein cholesterol, apolipoprotein B, triglycerides, and lipid ratios in relation to residual vascular risk after treatment with potent statin therapy: JUPITER (justification for the use of statins in prevention: an intervention trial evaluating rosuvastatin).

J Am Coll Cardiol 2012;59:1521-8

Mora S, Glynn RJ, Boekholdt SM, Nordestgaard BG, Kastelein JJ, Ridker PM
Inflammation Lipids/Lipoproteins
Key Publications July 19, 2012

Increased LCAT activity and hyperglycaemia decrease the antioxidative functionality of HDL.

Eur J Clin Invest 2012;42:487-95

Kappelle PJ, de Boer JF, Perton FG, Annema W, de Vries R, Dullaart RP, Tietge UJ
Diabetes Lipids/Lipoproteins Metabolism: Human Studies
Key Publications July 17, 2012

Metabolite profiling as a future tool in the prediction of type 2 diabetes mellitus.

Clin Endocrinol (Oxf) 2012;76:615-6

Karakas M, Koenig W
Diabetes Inflammation Lipids/Lipoproteins
Key Publications July 17, 2012

Evidence-based use of statins for primary prevention of cardiovascular disease.

Am J Med 2012;125:440-6

Minder CM, Blaha MJ, Horne A, Michos ED, Kaul S, Blumenthal RS
Lipids/Lipoproteins Prevention
Key Publications July 16, 2012

The association of specific metabolites of lipid metabolism with markers of oxidative stress, inflammation and arterial stiffness in men with newly diagnosed type 2 diabetes.

Clin Endocrinol (Oxf) 2012;76:674-82

Ha CY, Kim JY, Paik JK, Kim OY, Paik YH, Lee EJ, Lee JH
Diabetes Inflammation Lipids/Lipoproteins
Key Publications July 16, 2012

Risk prediction measures for case-cohort and nested case-control designs: an application to cardiovascular disease.

Am J Epidemiol 2012;175:715-24

Ganna A, Reilly M, de Faire U, Pedersen N, Magnusson P, Ingelsson E
Epidemiology Lipids/Lipoproteins
Key Publications July 10, 2012

Association of LDL cholesterol, non-HDL cholesterol, and apolipoprotein B levels with risk of cardiovascular events among patients treated with statins: a meta-analysis.

JAMA 2012;307:1302-9

Boekholdt SM, Arsenault BJ, Mora S, Pedersen TR, LaRosa JC, Nestel PJ, Simes RJ, Durrington P, Hitman GA, Welch KM, DeMicco DA, Zwinderman AH, Clearfield MB, Downs JR, Tonkin AM, Colhoun HM, Gotto AM Jr, Ridker PM, Kastelein JJ
Epidemiology Lipids/Lipoproteins
Key Publications July 6, 2012

Lipoprotein-associated phospholipase A2 mass and activity and risk of cardiovascular disease in a population with high prevalences of obesity and diabetes: the strong heart study.

Diabetes Care 2012;35:840-7

Kizer JR, Umans JG, Zhu J, Devereux RB, Wolfert RL, Lee ET, Howard BV
Diabetes Lipids/Lipoproteins Obesity
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