Documentation centre

Arner P, Bernard S, Salehpour M, Possnert G, Liebl J, Steier P, Buchholz BA, Eriksson M, Arner E, Hauner H, Skurk T, Rydén M, Frayn KN, Spalding KL

Adipose Tissue Lipids/Lipoproteins Metabolism: Human Studies

Key Publications January 16, 2012

Mechanism of action of a peroxisome proliferator-activated receptor (PPAR)-delta agonist on lipoprotein metabolism in dyslipidemic subjects with central obesity.

J Clin Endocrinol Metab 2011;96:E1568-76

Ooi EM, Watts GF, Sprecher DL, Chan DC, Barrett PH

Abdominal Obesity/Body Fat Distribution Lipids/Lipoproteins Metabolism: Human Studies

Key Publications January 16, 2012

Consumption of fructose and high fructose corn syrup increase postprandial triglycerides, LDL-cholesterol, and apolipoprotein-B in young men and women.

J Clin Endocrinol Metab 2011;96:E1596-605

Stanhope KL, Bremer AA, Medici V, Nakajima K, Ito Y, Nakano T, Chen G, Fong TH, Lee V, Menorca RI, Keim NL, Havel PJ

Lipids/Lipoproteins Nutrition

Key Publications January 9, 2012

The Anglo-Scandinavian Cardiac Outcomes Trial: 11-year mortality follow-up of the lipid-lowering arm in the UK.

Eur Heart J 2011;32:2525-32

Sever PS, Chang CL, Gupta AK, Whitehouse A, Poulter NR, on behalf of the ASCOT Investigators

Hypertension Lipids/Lipoproteins

Key Publications January 6, 2012

LDL from obese patients with the metabolic syndrome show increased lipid peroxidation and activate platelets.

Diabetologia 2011;54:2931-40

Colas R, Sassolas A, Guichardant M, Cugnet-Anceau C, Moret M, Moulin P, Lagarde M, Calzada C

Lipids/Lipoproteins Metabolic Syndrome Obesity

Key Publications January 6, 2012

Change in high-density lipoprotein cholesterol and risk of subsequent hospitalization for coronary artery disease or stroke among patients with type 2 diabetes mellitus.

Am J Cardiol 2011;108:1124-8

Nichols GA, Vupputuri S, Rosales AG

Diabetes Lipids/Lipoproteins

Key Publications January 3, 2012

Similar VLDL-TG storage in visceral and subcutaneous fat in obese and lean women.

Diabetes 2011;60:2787-91

Søndergaard E, Nellemann B, Sørensen LP, Gormsen LC, Christiansen JS, Ernst E, Dueholm M, Nielsen S

Abdominal Obesity/Body Fat Distribution Lipids/Lipoproteins Obesity

Key Publications January 3, 2012

Vitamin D, insulin secretion, sensitivity, and lipids: results from a case-control study and a randomized controlled trial using hyperglycemic clamp technique.

Diabetes 2011;60:2748-57

Grimnes G, Figenschau Y, Almås B, Jorde R

Insulin Resistance Lipids/Lipoproteins Nutrition

Key Publications December 30, 2011

The cholesterol content of Western diets plays a major role in the paradoxical increase in high-density lipoprotein cholesterol and upregulates the macrophage reverse cholesterol transport pathway.

Arterioscler Thromb Vasc Biol 2011;31:2493-9

Escolà-Gil JC, Llaverias G, Julve J, Jauhiainen M, Méndez-González J, Blanco-Vaca F

Lipids/Lipoproteins Metabolism: Animal Studies Nutrition

Key Publications December 26, 2011

Effect of three consecutive meals on the physicochemical properties of HDL and LDL in individuals with the metabolic syndrome and patients with type 2 diabetes.

Eur J Clin Nutr 2011;65:1242-9

Scheffer PG, Tushuizen ME, Vermue HP, Schindhelm RK, Rustemeijer C, Diamant M

Diabetes Lipids/Lipoproteins Nutrition

Key Publications December 21, 2011

Risk for cardiovascular events in an Italian population of patients with type 2 diabetes.

Nutr Metab Cardiovasc Dis 2011;21:885-92

Pellegrini E, Maurantonio M, Giannico IM, Simonini MS, Ganazzi D, Carulli L, D'Amico R, Baldini A, Loria P, Bertolotti M, Carulli N