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Key Publications December 16, 2019

Intermuscular adipose tissue directly modulates skeletal muscle insulin sensitivity in humans.

Am J Physiol Endocrinol Metab. 2019;316:E866-E879

Sachs S, Zarini S, Kahn DE, Harrison KA, Perreault L, Phang T, Newsom SA, Strauss A, Kerege A, Schoen JA, Bessesen DH, Schwarzmayr T, Graf E, Lutter D, Krumsiek J, Hofmann SM, Bergman BC
Abdominal Obesity/Body Fat Distribution Ectopic Fat Insulin Resistance
Key Publications November 19, 2019

Insulin action is severely impaired in adipocytes of apparently healthy overweight and obese subjects.

J Intern Med. 2019;285:578-588

Rydén M, Petrus P, Andersson DP, Medina-Gómez G, Escasany E, Corrales Cordón P, Dahlman I, Kulyté A, Arner P.
Adipose Tissue Insulin Resistance Obesity
Key Publications November 1, 2019

Different acute effects of fructose and glucose administration on hepatic fat content.

Am J Clin Nutr. 2019;109:1519-1526

Dusilová T, Kovář J, Drobný M, Šedivý P, Dezortová M, Poledne R, Zemánková K, Hájek M
Ectopic Fat Insulin Resistance Nutrition
Key Publications October 30, 2019

Effects of branched-chain amino acids on glucose metabolism in obese, prediabetic men and women: a randomized, crossover study.

Am J Clin Nutr. 2019;109:1569-1577

Woo SL, Yang J, Hsu M, Yang A, Zhang L, Lee RP, Gilbuena I, Thames G, Huang J, Rasmussen A, Carpenter CL, Henning SM, Heber D, Wang Y, Li Z
Clinical Trials Insulin Resistance Obesity
Key Publications October 30, 2019

The effect of high compared with low dairy consumption on glucose metabolism, insulin sensitivity, and metabolic flexibility in overweight adults: a randomized crossover trial.

Am J Clin Nutr. 2019;109:1555-1568

Eelderink C, Rietsema S, van Vliet IMY, Loef LC, Boer T, Koehorst M, Nolte IM, Westerhuis R, Singh-Povel CM, Geurts JMW, Corpeleijn E, Bakker SJL
Insulin Resistance Nutrition Obesity
Key Publications October 29, 2019

Yogurt improves insulin resistance and liver fat in obese women with nonalcoholic fatty liver disease and metabolic syndrome: a randomized controlled trial.

Am J Clin Nutr. 2019;109:1611-1619

Chen Y, Feng R, Yang X, Dai J, Huang M, Ji X, Li Y, Okekunle AP, Gao G, Onwuka JU, Pang X, Wang C, Li C, Li Y, Sun C
Ectopic Fat Insulin Resistance Nutrition
Key Publications October 24, 2019

The role of visceral adiposity index levels in predicting the presence of metabolic syndrome and insulin resistance in overweight and obese patients.

Metab Syndr Relat Disord. 2019;17:296-302

Pekgor S, Duran C, Berberoglu U, Eryilmaz MA
Abdominal Obesity/Body Fat Distribution Insulin Resistance Metabolic Syndrome
Key Publications October 22, 2019

The effect of frequency of activity interruptions in prolonged sitting on postprandial glucose metabolism: A randomized crossover trial.

Metabolism. 2019;96:1-7

Thorsen IK, Johansen MY, Pilmark NS, Jespersen NZ, Brinkløv CF, Benatti FB, Dunstan DW, Karstoft K, Pedersen BK, Ried-Larsen M
Insulin Resistance Nutrition Physical Activity/Exercise
Key Publications October 21, 2019

Increased central adiposity and decreased subcutaneous adipose tissue 11β-hydroxysteroid dehydrogenase type 1 are associated with deterioration in glucose tolerance-A longitudinal cohort study.

Clin Endocrinol (Oxf). 2019;91:72-81

Crowley RK, Woods CP, Hughes BA, Gray J, McCarthy T, Taylor AE, Gathercole LL, Shackleton CHL, Crabtree N, Arlt W, Stewart PM, Tomlinson JW
Abdominal Obesity/Body Fat Distribution Insulin Resistance Steroid Hormones
Key Publications October 18, 2019

Independent relationships between bone mineral density, regional body fat and insulin sensitivity in white males.

Clin Endocrinol (Oxf). 2019;91:63-71

Loh WJ, Stevenson JC, Godsland IF
Abdominal Obesity/Body Fat Distribution Adipose Tissue Insulin Resistance
Expert Opinions September 25, 2019

As a clinician, could you comment on the gap between clinical approaches and population-based approaches to manage/prevent type 2 diabetes?

Gillian Booth, MD, MSc, FRCPC, Associate Professor, Department of Medicine, University of Toronto; Adjunct Scientist, Institute for Clinical Evaluative Sciences, Toronto, ON, Canada
Diabetes Insulin Resistance Prevention
Key Publications September 23, 2019

Metabolic implications of diet and energy intake during physical inactivity.

Med Sci Sports Exerc. 2019;51:995-1005

Winn NC, Pettit-Mee R, Walsh LK, Restaino RM, Ready ST, Padilla J, Kanaley JA
Insulin Resistance Nutrition Physical Activity/Exercise
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