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Expert Opinions June 7, 2017

Could you briefly describe the PREDIMED-PLUS study currently underway?

Emilios Ros, MD, PhD, Director, Lipid Clinic; Senior Consultant, Endocrinology and Nutrition Service, Hospital Clínic, Barcelona, Spain
Abdominal Obesity/Body Fat Distribution Metabolic Syndrome Nutrition
Key Publications June 6, 2017

Visceral adiposity and metabolic syndrome after very high-fat and low-fat isocaloric diets: a randomized controlled trial.

Am J Clin Nutr. 2017;105:85-99

Veum VL, Laupsa-Borge J, Eng Ø, Rostrup E, Larsen TH, Nordrehaug JE, Nygård OK, Sagen JV, Gudbrandsen OA, Dankel SN, Mellgren G
Ectopic Fat Metabolic Syndrome Nutrition
Key Publications June 5, 2017

Heritability of the severity of the metabolic syndrome in whites and blacks in 3 large cohorts.

Circ Cardiovasc Genet. 2017;10:e001621

Musani SK, Martin LJ, Woo JG, Olivier M, Gurka MJ, DeBoer MD
Ethnicity Metabolic Syndrome Sex Differences
Key Publications May 31, 2017

Oxidized LDL is associated with metabolic syndrome traits independently of central obesity and insulin resistance.

Diabetes. 2017;66:474-482

Hurtado-Roca Y, Bueno H, Fernandez-Ortiz A, Ordovas JM, Ibañez B, Fuster V, Rodriguez-Artalejo F, Laclaustra M
Abdominal Obesity/Body Fat Distribution Lipids/Lipoproteins Metabolic Syndrome
Key Publications May 12, 2017

An association of metabolic syndrome and chronic kidney disease from a 10-year prospective cohort study.

Metabolism. 2017;67:54-61

Huh JH, Yadav D, Kim JS, Son JW, Choi E, Kim SH, Shin C, Sung KC, Kim JY
Epidemiology Insulin Resistance Metabolic Syndrome
Key Publications May 11, 2017

A microbial protein that alleviates metabolic syndrome.

Nat Med. 2017 23:11-12

Anhê FF, Marette A
Metabolic Syndrome Metabolism: Human Studies Obesity
Key Publications May 9, 2017

Inflammatory mechanisms linking obesity and metabolic disease.

J Clin Invest. 2017;127:1-4

Saltiel AR, Olefsky JM
Inflammation Metabolic Syndrome Obesity
Key Publications April 5, 2017

Non-alcoholic fatty liver disease with and without metabolic syndrome: Different long-term outcomes.

Metabolism. 2017;66:55-63

Käräjämäki AJ, Bloigu R, Kauma H, Kesäniemi YA, Koivurova OP, Perkiömäki J, Huikuri H, Ukkola O
Cardiovascular Disease Ectopic Fat Metabolic Syndrome
Key Publications April 5, 2017

Nonalcoholic fatty liver disease: Updates on associations with the metabolic syndrome and lipid profile and effects of treatment with PPAR-g agonists.

Metabolism. 2017;66:64-68

Polyzos SA, Bugianesi E, Kountouras J, Mantzoros CS
Ectopic Fat Lipids/Lipoproteins Metabolic Syndrome
Key Publications April 4, 2017

Characteristics of metabolic syndrome in morbidly obese subjects.

Metab Syndr Relat Disord. 2016;14:500-506

Dusanov S, Heggen E, Tonstad S
Abdominal Obesity/Body Fat Distribution Metabolic Syndrome Obesity
Key Publications April 4, 2017

Obesity is more closely related with hepatic steatosis and fibrosis measured by transient elastography than metabolic health status.

Metabolism. 2017;66:23-31

Huh JH, Kim KJ, Kim SU, Han SH, Han KH, Cha BS, Chung CH, Lee BW
Ectopic Fat Metabolic Syndrome Obesity
Key Publications April 3, 2017

Determinants of improvement in left ventricular diastolic function following a 1-year lifestyle modification program in abdominally obese men with features of the metabolic syndrome.

Metab Syndr Relat Disord. 2016;14:483-491

Leclerc J, Arsenault M, Després JP, Brassard P, Gaudreault V, Bergeron J, Alméras N, Tremblay A, Auclair A, Ross MK, Denault-Bissonnette S, Poirier P
Abdominal Obesity/Body Fat Distribution Cardiovascular Disease Metabolic Syndrome
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