Documentation centre

Sachs S, Zarini S, Kahn DE, Harrison KA, Perreault L, Phang T, Newsom SA, Strauss A, Kerege A, Schoen JA, Bessesen DH, Schwarzmayr T, Graf E, Lutter D, Krumsiek J, Hofmann SM, Bergman BC

Expert Opinions December 4, 2019

Could you tell us why the liver is such a central and key organ in the etiology of the atherogenic dyslipidemia associated with excess visceral adiposity?

Marja-Riitta Taskinen, MD, PhD, Emerita Professor of Medicine, Research Programs Unit, Diabetes and Obesity, University of Helsinki, Helsinki University Hospital, Helsinki, Finland

Abdominal Obesity/Body Fat Distribution Ectopic Fat Lipids/Lipoproteins

Key Publications November 28, 2019

Physical activity and sedentary time: association with metabolic health and liver fat.

Med Sci Sports Exerc. 2019;51:1169-1177

Bowden Davies KA, Sprung VS, Norman JA, Thompson A, Mitchell KL, Harrold JOA, Finlayson G, Gibbons C, Wilding JPH, Kemp GJ, Hamer M, Cuthbertson DJ

Ectopic Fat Metabolic Syndrome Physical Activity/Exercise

Key Publications November 1, 2019

Different acute effects of fructose and glucose administration on hepatic fat content.

Am J Clin Nutr. 2019;109:1519-1526

Dusilová T, Kovář J, Drobný M, Šedivý P, Dezortová M, Poledne R, Zemánková K, Hájek M

Ectopic Fat Insulin Resistance Nutrition

Key Publications October 29, 2019

Yogurt improves insulin resistance and liver fat in obese women with nonalcoholic fatty liver disease and metabolic syndrome: a randomized controlled trial.

Am J Clin Nutr. 2019;109:1611-1619

Chen Y, Feng R, Yang X, Dai J, Huang M, Ji X, Li Y, Okekunle AP, Gao G, Onwuka JU, Pang X, Wang C, Li C, Li Y, Sun C

Ectopic Fat Insulin Resistance Nutrition

Key Publications October 28, 2019

PCSK7 gene variation bridges atherogenic dyslipidemia with hepatic inflammation in NAFLD patients.

J Lipid Res. 2019;60:1144-1153

Dongiovanni P, Meroni M, Baselli G, Mancina RM, Ruscica M, Longo M, Rametta R, Cespiati A, Pelusi S, Ferri N, Ranzani V, Nobili V, Pihlajamaki J, Fracanzani AL, Badiali S, Petta S, Fargion S, Romeo S, Kozlitina J, Valenti L

Ectopic Fat Genetics Inflammation

Key Publications October 21, 2019

Fatty liver in lipodystrophy: A review with a focus on therapeutic perspectives of adiponectin and/or leptin replacement.

Metabolism. 2019;96:66-82

Polyzos SA, Perakakis N, Mantzoros CS

Adipokines Ectopic Fat Prevention

Key Publications October 9, 2019

Temporal changes in body fat distribution and hypertension.

J Am Coll Cardiol. 2019;73:3357-3359

Chandra A, Ayers CR, Neeland IJ

Abdominal Obesity/Body Fat Distribution Ectopic Fat Hypertension

Key Publications September 19, 2019

Cardiovascular disease in chronic respiratory disorders and beyond.

J Am Coll Cardiol. 2019;73:2178-2180

Rogliani P, Cazzola M, Calzetta L

Cardiovascular Disease Ectopic Fat Respiratory Diseases

Key Publications September 19, 2019

Ectopic fat and aerobic fitness are key determinants of glucose homeostasis in nonobese Asians.

Eur J Clin Invest. 2019;49:e13079

Chan Z, Ding C, Chooi YC, Choo J, Sadananthan SA, Sasikala S, Chang A, Michael N, Velan SS, Leow MK, Magkos F

Ectopic Fat Insulin Resistance Physical Activity/Exercise

Key Publications August 29, 2019

Consumption of alcoholic and sugar-sweetened beverages is associated with increased liver fat content in middle-aged men and women.

J Nutr. 2019;149:649-658

van Eekelen E, Beulens JWJ, Geelen A, Schrauwen-Hinderling VB, Lamb H, de Roos A, Rosendaal F, de Mutsert R

Ectopic Fat Nutrition Prevention

Key Publications August 14, 2019

Gut microbial metabolites in obesity, NAFLD and T2DM.

Nat Rev Endocrinol. 2019;15:261-273

Canfora EE, Meex RCR, Venema K, Blaak EE

Diabetes Ectopic Fat Obesity

Intermuscular adipose tissue directly modulates skeletal muscle insulin sensitivity in humans.

Am J Physiol Endocrinol Metab. 2019;316:E866-E879