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Key Publications February 9, 2018

Effect of adding bezafibrate to standard lipid-lowering therapy on post-fat load lipid levels in patients with familial dysbetalipoproteinemia. A randomized placebo-controlled crossover trial.

J Lipid Res. 2017;58:2180-2187

Koopal C, Marais AD, Westerink J, van der Graaf Y, Visseren FLJ
Genetics Lipids/Lipoproteins Nutrition
Key Publications February 8, 2018

Epigenetic programming, early life nutrition and the risk of metabolic disease.

Atherosclerosis. 2017;266:31-40

Block T, El-Osta A
Diabetes Genetics Nutrition
Key Publications February 1, 2018

A Mendelian randomization study of metabolite profiles, fasting glucose, and type 2 diabetes.

Diabetes. 2017;66:2915-2926

Liu J, van Klinken JB, Semiz S, van Dijk KW, Verhoeven A, Hankemeier T, Harms AC, Sijbrands E, Sheehan NA, van Duijn CM, Demirkan A
Diabetes Genetics Lipids/Lipoproteins
Key Publications January 31, 2018

An expanded genome-wide association study of type 2 diabetes in Europeans.

Diabetes. 2017;66:2888-2902

Scott RA, Scott LJ, Mägi R, Marullo L, Gaulton KJ, Kaakinen M, Pervjakova N et al.
Diabetes Epidemiology Genetics
Key Publications January 25, 2018

New blood pressure-associated loci identified in meta-analyses of 475000 individuals.

Circ Cardiovasc Genet. 2017;10;e001778

Kraja AT, Cook JP, Warren HR, Surendran P, Liu C, Evangelou E, Manning AK et al.
Epidemiology Genetics Hypertension
Key Publications January 9, 2018

Number of offspring and cardiovascular disease risk in men and women: The role of shared lifestyle characteristics.

Epidemiology. 2017;28:880-888

Magnus MC, Iliodromiti S, Lawlor DA, Catov JM, Nelson SM, Fraser A
Cardiovascular Disease Genetics Sex Differences
Key Publications December 21, 2017

Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.

PLoS Genet. 2017;13:e1006528

Graff M, Scott RA, Justice AE, Young KL, Feitosa MF, Barata L, Winkler TW, Chu AY, Mahajan A, Hadley D, Xue L, Workalemahu T et al.
Genetics Obesity Physical Activity/Exercise
Key Publications December 8, 2017

The impact of APOA5, APOB, APOC3 and ABCA1 gene polymorphisms on ischemic stroke: Evidence from a meta-analysis.

Atherosclerosis. 2017;265:60-70

Au A, Griffiths LR, Irene L, Kooi CW, Wei LK
Cardiovascular Disease Genetics Lipids/Lipoproteins
Key Publications December 4, 2017

Genetic susceptibility, change in physical activity, and long-term weight gain.

Diabetes. 2017;66:2704-2712

Wang T, Huang T, Heianza Y, Sun D, Zheng Y, Ma W, Jensen MK, Kang JH, Wiggs JL, Pasquale LR, Rimm EB, Manson JE, Hu FB, Willett WC, Qi L
Genetics Obesity Physical Activity/Exercise
Key Publications November 23, 2017

A genome-wide association meta-analysis on lipoprotein (a) concentrations adjusted for apolipoprotein (a) isoforms.

J Lipid Res. 2017;58:1834-1844

Mack S, Coassin S, Rueedi R, Yousri NA, Seppälä I, Gieger C, Schönherr S et al.
Cardiovascular Disease Genetics Lipids/Lipoproteins
Key Publications November 16, 2017

Low-density lipoproteins cause atherosclerotic cardiovascular disease. 1. Evidence from genetic, epidemiologic, and clinical studies. A consensus statement from the European Atherosclerosis Society Consensus Panel.

Eur Heart J. 2017;38:2459-2472

Ference BA, Ginsberg HN, Graham I, Ray KK, Packard CJ, Bruckert E, Hegele RA et al.
Cardiovascular Disease Genetics Lipids/Lipoproteins
Key Publications November 14, 2017

Effect of the interaction between diet composition and the PPM1K genetic variant on insulin resistance and Beta cell function markers during weight loss: results from the Nutrient Gene Interactions in Human Obesity: implications for dietary guidelines (NUGENOB) randomized trial.

Am J Clin Nutr. 2017;106:902-908

Goni L, Qi L, Cuervo M, Milagro FI, Saris WH, MacDonald IA, Langin D, Astrup A, Arner P, Oppert JM, Svendstrup M, Blaak EE, Sørensen TI, Hansen T, Martínez JA
Genetics Insulin Resistance Weight Loss
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