Documentation centre

Hivert MF, Christophi CA, Franks PW, Jablonski KA, Ehrmann DA, Kahn SE, Horton ES, Pollin TI, Mather KJ, Perreault L, Barrett-Connor E, Knowler WC, Florez JC, Diabetes Prevention Program Research Group

Genetics Insulin Resistance Physical Activity/Exercise

Key Publications March 14, 2016

Genetics of CVD in 2015: Using genomic approaches to identify CVD-causing variants.

Nat Rev Cardiol. 2016;13:72-4

Arnett DK

Cardiovascular Disease Genetics Prevention

Key Publications January 25, 2016

Differential genetic effects on statin-induced changes across low-density lipoprotein-related measures.

Circ Cardiovasc Genet. 2015;8:688-95

Chu AY, Giulianini F, Barratt BJ, Ding B, Nyberg F, Mora S, Ridker PM, Chasman DI

Cardiovascular Disease Genetics Lipids/Lipoproteins

Key Publications January 21, 2016

Decade in review-type 2 diabetes mellitus: At the centre of things.

Nat Rev Endocrinol. 2015;11:636-8

Ning G

Diabetes Genetics Insulin Resistance

Key Publications January 21, 2016

Obesity: Gut microbiota, host genetics and diet interact to affect the risk of developing obesity and the metabolic syndrome.

Nat Rev Endocrinol. 2015;11:630

Greenhill C

Genetics Metabolic Syndrome Obesity

Key Publications December 21, 2015

The relation between the presence of cardiovascular disease and vascular risk factors in offspring and the occurrence of new vascular events in their parents already at high vascular risk.

Am Heart J. 2015;170:744-752

Weijmans M, van der Graaf Y, de Borst GJ, Asselbergs FW, Cramer MJ, Algra A, Visseren FL, SMART study group

Cardiovascular Disease Diabetes Genetics

Key Publications December 18, 2015

Association between CETP gene polymorphism, insulin resistance and risk of diabetes mellitus in patients with vascular disease.

Atherosclerosis. 2015;242:605-10

Koopal C, van der Graaf Y, Asselbergs FW, Westerink J, Visseren FL, SMART study group

Diabetes Genetics Insulin Resistance

Do genes determine our health? Implications for designing lifestyle interventions and drug trials.

Circ Cardiovasc Genet. 2016;9:2-3

Differential effects of leptin on adiponectin expression with weight gain versus obesity.

Int J Obes (Lond). 2016;40:266-74

Inverse relationship between a genetic risk score of 31 BMI loci and weight change before and after reaching middle age.

Int J Obes (Lond). 2016;40:252-9

Apolipoprotein E4 association with metabolic syndrome depends on body fatness.

Atherosclerosis. 2016;245:35-42

Numerous genes in loci associated with body fat distribution are linked to adipose function.

Diabetes. 2016;65:433-7

Lifestyle and metformin ameliorate insulin sensitivity independently of the genetic burden of established insulin resistance variants in Diabetes Prevention Program participants.

Diabetes. 2016;65:520-6