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Key Publications April 3, 2012

IL-1 and atherosclerosis: a murine twist to an evolving human story.

J Clin Invest 2012;122:27-30

Rader DJ
Inflammation Metabolism: Animal Studies
Key Publications April 3, 2012

Genetic inactivation of IL-1 signaling enhances atherosclerotic plaque instability and reduces outward vessel remodeling in advanced atherosclerosis in mice.

J Clin Invest 2012;122:70-9

Alexander MR, Moehle CW, Johnson JL, Yang Z, Lee JK, Jackson CL, Owens GK
Inflammation Metabolism: Animal Studies
Key Publications January 26, 2012

Evacetrapib is a novel, potent, and selective inhibitor of cholesteryl ester transfer protein that elevates HDL cholesterol without inducing aldosterone or increasing blood pressure.

J Lipid Res 2011;52:2169-76

Cao G, Beyer TP, Zhang Y, Schmidt RJ, Chen YQ, Cockerham SL, Zimmerman KM, Karathanasis SK, Cannady EA, Fields T, Mantlo NB
Hypertension Lipids/Lipoproteins Metabolism: Animal Studies
Key Publications January 26, 2012

Nascent HDL formation by hepatocytes is reduced by the concerted action of serum amyloid A and endothelial lipase.

J Lipid Res 2011;52:2255-61

Wroblewski JM, Jahangiri A, Ji A, de Beer FC, van der Westhuyzen DR, Webb NR
Inflammation Lipids/Lipoproteins Metabolism: Animal Studies
Key Publications January 19, 2012

Adipose tissue ATP binding cassette transporter A1 contributes to high-density lipoprotein biogenesis in vivo.

Circulation 2011;124:1663-72

Chung S, Sawyer JK, Gebre AK, Maeda N, Parks JS
Adipose Tissue Lipids/Lipoproteins Metabolism: Animal Studies
Key Publications January 5, 2012

Transplantation of non-visceral fat to the visceral cavity improves glucose tolerance in mice: investigation of hepatic lipids and insulin sensitivity.

Diabetologia 2011;54:2890-9

Foster MT, Shi H, Softic S, Kohli R, Seeley RJ, Woods SC
Abdominal Obesity/Body Fat Distribution Insulin Resistance Metabolism: Animal Studies
Key Publications December 30, 2011

The cholesterol content of Western diets plays a major role in the paradoxical increase in high-density lipoprotein cholesterol and upregulates the macrophage reverse cholesterol transport pathway.

Arterioscler Thromb Vasc Biol 2011;31:2493-9

Escolà-Gil JC, Llaverias G, Julve J, Jauhiainen M, Méndez-González J, Blanco-Vaca F
Lipids/Lipoproteins Metabolism: Animal Studies Nutrition
Key Publications December 8, 2011

Large size cells in the visceral adipose depot predict insulin resistance in the canine model.

Obesity (Silver Spring) 2011;19:2121-9

Kabir M, Stefanovski D, Hsu IR, Iyer M, Woolcott OO, Zheng D, Catalano KJ, Chiu JD, Kim SP, Harrison LN, Ionut V, Lottati M, Bergman RN, Richey JM
Abdominal Obesity/Body Fat Distribution Insulin Resistance Metabolism: Animal Studies
Key Publications December 5, 2011

Perivascular visceral adipose tissue induces atherosclerosis in apolipoprotein E deficient mice.

Atherosclerosis 2011;219:33-9

Ohman MK, Luo W, Wang H, Guo C, Abdallah W, Russo HM, Eitzman DT
Abdominal Obesity/Body Fat Distribution Lipids/Lipoproteins Metabolism: Animal Studies
Key Publications November 15, 2011

Mechanisms of myocardial infarction in women without angiographically obstructive coronary artery disease.

Circulation 2011;124:1414-25

Reynolds HR, Srichai MB, Iqbal SN, Slater JN, Mancini GB, Feit F, Pena-Sing I, Axel L, Attubato MJ, Yatskar L, Kalhorn RT, Wood DA, Lobach IV, Hochman JS
Interventional Cardiology Metabolism: Animal Studies
Key Publications September 28, 2011

Mechanisms regulating hepatic SR-BI expression and their impact on HDL metabolism.

Atherosclerosis 2011;217:299-307

Leiva A, Verdejo H, Benítez ML, Martínez A, Busso D, Rigotti A
Lipids/Lipoproteins Metabolism: Animal Studies Metabolism: Human Studies
Key Publications July 28, 2011

Metabolic and functional relevance of HDL subspecies.

Curr Opin Lipidol 2011;22:176-85

Asztalos BF, Tani M, Schaefer EJ
Interventional Cardiology Metabolism: Animal Studies Metabolism: Human Studies
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