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Key Publications April 8, 2008

Increased fat accumulation in liver may link insulin resistance with subcutaneous abdominal adipocyte enlargement, visceral adiposity, and hypoadiponectinemia in obese individuals.

Am J Clin Nutr 2008;87:295-302

Koska J, Stefan N, Permana PA et al.
Ectopic Fat
Key Publications April 4, 2008

Progressive caloric restriction induces dose-dependent changes in myocardial triglyceride content and diastolic function in healthy men.

J Clin Endocrinol Metab 2008;93:497-503

Hammer S, van der Meer RW, Lamb HJ et al.
Ectopic Fat
Key Publications April 4, 2008

Pericardial fat, visceral abdominal fat, cardiovascular disease risk factors, and vascular calcification in a community-based sample: the Framingham Heart Study.

Circulation 2008;117:605-13

Rosito GA, Massaro JM, Hoffmann U et al.
Ectopic Fat
Key Publications February 28, 2008

Liver fat is increased in type 2 diabetic patients and underestimated by serum alanine aminotransferase compared with equally obese nondiabetic subjects.

Diabetes Care 2008;31:165-9

Kotronen A, Juurinen L, Hakkarainen A
Ectopic Fat
Key Publications February 28, 2008

Fatty liver: a novel component of the metabolic syndrome.

Arterioscler Thromb Vasc Biol 2008;28:27-38

Kotronen A, Yki-Järvinen H
Ectopic Fat
Key Publications February 28, 2008

Rosiglitazone reduces liver fat and insulin requirements and improves hepatic insulin sensitivity and glycemic control in patients with type 2 diabetes requiring high insulin doses.

J Clin Endocrinol Metab 2008;93:118-24

Juurinen L, Kotronen A, Granér M, Yki-Järvinen H
Ectopic Fat
Key Publications February 11, 2008

Tissue specificity of insulin resistance in humans: fat in the liver rather than muscle is associated with features of the metabolic syndrome.

Diabetologia 2008;5:130-8

Kotronen A, Seppälä-Lindroos A, Bergholm R, Yki-Järvinen H
Ectopic Fat
Key Publications February 11, 2008

Increased intrahepatic triglyceride is associated with peripheral insulin resistance: in vivo MR imaging and spectroscopy studies.

Am J Physiol Endocrinol Metab 2007;293:E1663-9

Hwang JH, Stein DT, Barzilai N et al.
Ectopic Fat
Key Publications February 11, 2008

Serum retinol-binding protein-4, leptin, and adiponectin concentrations are related to ectopic fat accumulation.

J Clin Endocrinol Metab 2007;92:4883-8

Perseghin G, Lattuada G, De Cobelli F et al.
Ectopic Fat
Key Publications January 29, 2008

Lipodystrophy in HIV 1-infected patients: lessons for obesity research.

Int J Obes (Lond) 2007;31:1763-76

Villarroya F, Domingo P, Giralt M
Ectopic Fat
Key Publications November 19, 2007

Acute suppression of VLDL(1) secretion rate by insulin is associated with hepatic fat content and insulin resistance.

Diabetologia 2007;50:2356-65

Adiels M, Westerbacka J, Soro-Paavonen A et al.
Ectopic Fat
Key Publications October 30, 2007

Fatty liver-based identification of two distinct hypertriglyceridemic subgroups in familial combined hyperlipidemia.

Metabolism 2007;56:1311-7

Brouwers MC, van Greevenbroek MM, Bilderbeek-Beckers MA et al.
Ectopic Fat
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