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Key Publications September 22, 2010

Is the recent rise in type 2 diabetes incidence from 1984 to 2007 explained by the trend in increasing BMI?: Evidence from a prospective study of British men.

Diabetes Care 2010;33:1494-6

Hardoon SL, Morris RW, Thomas MC, Wannamethee SG, Lennon LT, Whincup PH

Description

This brief report sought to estimate the impact of the increasing body mass index (BMI) observed in the population on the simultaneous growth in type 2 diabetes incidence in the UK. The authors analyzed a representative cohort of 6,460 British men over a 24-year follow-up period for type 2 diabetes incidence. The data showed that increasing adiposity appeared to explain almost a quarter of the rise in type 2 diabetes incidence in periods 1 (1984 to 1992) and 3 (1999 to 2007). Therefore, a large proportion of the rise in the incidence of type 2 diabetes remains unexplained. The authors highlighted other determinants of type 2 diabetes such as physical inactivity and poor dietary habits which must be examined in future time-trend studies.
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