Lipoprotein-associated phospholipase A2, high-sensitivity C-reactive protein, and risk for incident ischemic stroke in middle-aged men and women in the Atherosclerosis Risk in Communities (ARIC) study.

Description

Both lipoprotein-associated phospholipase A2 (Lp-PLA2) and C-reactive protein levels predicted incident ischemic stroke in a prospective case–cohort analysis from the Atherosclerosis Risk in Communities study. Even after adjusting for other cardiovascular risk factors, individuals with high levels of both Lp-PLA2 and C-reactive protein levels had increased stroke risk compared to individuals with low levels of both.