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Key Publications November 14, 2008

Risk prediction of cardiovascular disease in type 2 diabetes: a risk equation from the Swedish National Diabetes Register.

Diabetes Care 2008;31:2038-43

Cederholm J, Eeg-Olofsson K, Eliasson B et al.

Description

As there are few cardiovascular disease (CVD) risk prediction models specifically for patients with type 2 diabetes and since 5-year risk estimates have recently been suggested to be more accurate than 10-year risk estimates, this study presented a new risk equation for estimating the absolute 5-year CVD risk in the Swedish National Diabetes Register, which included 11,646 men and women with 1,482 first incident CVD events during the mean follow-up of 5.64 years. Variables incorporated into the risk equation were HbA1c, age at onset of diabetes, diabetes duration, sex, body mass index, smoking, systolic blood pressure, and antihypertensive and lipid-lowering drugs. The equation includes easily available clinical nonlaboratory variables and the measurement of only one nonfasting blood marker (HbA1C). Although the risk equation will have to be validated in other cohorts, its simplicity holds out promise for use in clinical practice.

Categories

Diabetes
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